Enhancing signal to noise ratio in DCS
Diffuse Correlation Spectroscopy (DCS) is a non-invasive technique that can be used to measure blood flow in tissue. This generally involves coupling laser light from a fibre into the tissue and measuring the scattered light at a distance from the input, also using a fibre.
How Duke University utilises the Photon Force PF32 for DCS
At Duke University, Wenhui Liu et al use the Photon Force PF32 SPAD camera’s high frame rates and photon counting mode to record single-photon images at over 300kfps.
In the paper ‘Fast sensitive diffuse correlation spectroscopy with a SPAD array’, the team at Duke detail how they developed a highly parallelized DCS system using the PF32’s 32 x 32 single-photon avalanche diode (SPAD) array and demonstrated its sensitivity improvement in a DMD-based study and an in vivo forehead blood flow experiment.