A camera with such precise timing resolution that it can watch light as it travels:
Researchers from Heriot-Watt University have exploited the PF32’s timing resolution to film laser pulse propagation in optical fibres in a number of different situations. The video below shows laser pulse tracking of a 1GHz pulse train. The paper can be found here: Observation of laser pulse propagation in optical fibers with a SPAD camera
No more scanning: time-resolved measurements with an array of single-photon detectors.
FLIM and FRET imaging traditionally use scanning systems to form an image of the sample under test. With the PF32, however, an image is formed without the need for scanning thanks to the 32 x 32 array of SPAD detectors in the sensor. The following video is an excerpt from S. Poland’s paper:
The PF32 system has been used in a wide range of research activities. A small selection of these high-profile publications is detailed below:
- A high speed multifocal multiphoton fluorescence lifetime imaging microscope for live-cell FRET imaging
Simon Poland et al., Biomedical Optics Express, 6 (2), 277-296, 2015.
- Multiplexed Single-Mode Wavelength-to-Time Mapping of Multimode Light
Harikumar Chandrasekharan et al., Nature Communications, 8, 14080, 2017.
- 0.5 billion events per second time correlated single photon counting using CMOS SPAD arrays
Nikola Krstajić et al., Optics Letters, 40 (18), 4305-4308, 2015.
- Time-resolved multifocal multiphoton microscope for high speed FRET imaging in vivo
Simon Poland et al., Optics Letters, 39 (20), 6013-6016, 2015.
- Single-photon sensitive light-in-flight imaging
Genevieve Gariepy et al., Nature Communications, 6, 6021, 2015.
- Detection and tracking of moving objects hidden from view
Genevieve Gariepy et al., Nature Photonics, 10 (1), 23-26, 2016.